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Article

Clinical and genetic analysis of Taiwanese patients with hereditary spastic paraplegia type 5.

European journal of neurology - 1 Jan 2015

Lan M-Y, Yeh T-H, Chang Y-Y, Kuo H-C, Sun H S, Lai S-C, Lu C-S

Abstract excerpt

BACKGROUND AND PURPOSE: Spastic paraplegia type 5 (SPG5) is an autosomal recessive (AR) hereditary spastic paraplegia (HSP) associated with pure or complicated phenotypes. This study aimed to screen SPG5 in Taiwanese HSP patients. METHODS: Sequencing of the SPG5 gene, CYP7B1, was performed in a cohort of 25 ethnic Han Taiwanese patients with AR or sporadic HSP. Clinical information and magnetic resonance imaging...

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PMID: 24641183
DOI: 10.1111/ene.12407

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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