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Article

Inhibition of microRNA miR-92a induces apoptosis and necrosis in human acute promyelocytic leukemia

1 Jan 2014

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are endogenous non-coding RNAs, 19-25 nucleotides in length, involved in post-transcriptional regulation of gene expression in a considerable majority of mRNAs. Different aspects of cellular activities like cell growth, proliferation, and differentiation are regulated by miRNAs through their regulatory effects on particular RNA species. In many tumors, up- or down-regulation of...

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PMID: 24627869
DOI: 10.4103/2277-9175.125826

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