Childhood abuse is associated with methylation of multiple loci in adult DNA

Abstract excerpt

BACKGROUND: Childhood abuse is associated with increased adult disease risk, suggesting that processes acting over the long-term, such as epigenetic regulation of gene activity, may be involved. DNA methylation is a critical mechanism in epigenetic regulation. We aimed to establish whether childhood abuse was associated with adult DNA methylation profiles. METHODS: In 40 males from the 1958 British Birth Cohort...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Child Abuse and Trauma
• Share to Epigenetics and DNA Methylation