Article
Tumor necrosis factor receptor-associated periodic syndrome managed with the couple canakinumab-alendronate.
Clinical rheumatology - 1 Apr 2015
Lopalco Giuseppe, Rigante Donato, Vitale Antonio, Frediani Bruno, Iannone Florenzo, Cantarini Luca
Abstract excerpt
Management of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is puzzling, and therapeutic choices can be complicated, due to both wide genetic heterogeneity and protean clinical phenotype. We report on a 35-year-old female who was diagnosed with TRAPS, after finding the V95M mutation on the TNFRSF1A gene; who was treated in order with etanercept, anakinra, and canakinumab (150 mg/every 8...
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