Article
[TNF receptor-associated periodic syndrome (TRAPS) in Japan: clinical characterization, pathogenesis, diagnostic criteria, and treatment].
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology - 1 Apr 2007
Ida Hiroaki, Eguchi Katsumi
Abstract excerpt
TNF receptor-associated periodic syndrome (TRAPS) is an autosomal dominant inherited disease characterized by prolonged episodes of periodic fever and localized inflammation. The hypothetical pathogenesis of TRAPS is defective TNF receptor 1 (TNFRSF1A) shedding from cell membranes in response to a stimulus including TNFalpha. This mechanism has recently been shown to account for a minor population of TRAPS...
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