Article
Canakinumab efficacy and long-term tocilizumab administration in tumor necrosis factor receptor-associated periodic syndrome (TRAPS).
Rheumatology international - 1 Nov 2015
La Torre Francesco, Muratore Maurizio, Vitale Antonio, Moramarco Fulvio, Quarta Laura, Cantarini Luca
Abstract excerpt
Tumor necrosis factor receptor-associated periodic syndrome (TRAPS) is an autosomal dominantly inherited autoinflammatory disease caused by mutations in the TNFRSF1A gene. Treatment is aimed at preventing acute disease attacks, improving quality of life, and preventing long-term complications such as systemic reactive amyloidosis. Biologic agents have significantly improved TRAPS management. In particular,...
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