MiRNA-125a-5p: a regulator and predictor of gefitinib’s effect on nasopharyngeal carcinoma

Abstract excerpt

BACKGROUND: Nasopharyngeal carcinoma (NPC) is a common malignancy in China and Southeast Asia. Radiotherapy is the major treatment modality for patients with NPC, but does not always achieve fully satisfactory outcomes. Studies have shown that epidermal growth factor receptor (EGFR) is highly expressed in NPC, and EGFR-targeted treatment is expected to be a new strategy for NPC. Recently, clinical trials have...

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