Article
A highly divergent 33 kDa Cryptosporidium parvum antigen.
The Journal of parasitology - 1 Aug 2014
Jenkins Mark C, Widmer Giovanni, O'Brien Celia, Bauchan Gary, Murphy Charles, Santin Monica, Fayer Ronald
Abstract excerpt
Previous studies comparing the genome sequences of Cryptosporidium parvum with Cryptosporidium hominis identified a number of highly divergent genes that might reflect positive selection for host specificity. In the present study, the C. parvum DNA sequence cgd8-5370, which encodes a protein whose amino acid sequence differs appreciably from its homologue in C. hominis , was cloned by PCR and expressed as a...
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