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The evolution of genes within genes and the control of DNA replication in microviruses.

Molecular biology and evolution - 1 Jun 2014

Doore Sarah M, Baird Cameron D, Roznowski Aaron P, Fane Bentley A

Abstract excerpt

Single-stranded DNA(ssDNA) viral life cycles must balance double-stranded DNA (dsDNA) and ssDNA biosynthesis. Previously published in vitro results suggest that microvirus C and host cell SSB proteins play antagonistic roles to achieve this balance. To investigate this in vivo, microvirus DNA replication was characterized in cells expressing cloned C or ssb genes, which would presumably alter the C:SSB protein...

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Identifiers

PMID: 24600050
DOI: 10.1093/molbev/msu089

Genes

SSB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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