Article
Mutations in the measles virus C protein that up regulate viral RNA synthesis.
Virology - 20 Jun 2001
Reutter G L, Cortese-Grogan C, Wilson J, Moyer S A
Abstract excerpt
The measles virus RNA-dependent RNA polymerase consists of two virus-encoded subunits, the phosphoprotein (P) and the large (L) protein. The P mRNA also codes for a C protein in the +1 reading frame relative to P. The activities of the measles P and C proteins from the vaccine strain, EdB, a wild-type CM strain, and an SSPE P4 strain were investigated using a CAT reporter minigenome assay. CAT is synthesized...
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