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Article

Th1 response and systemic treg deficiency in inclusion body myositis.

PloS one - 1 Jan 2014

Allenbach Yves, Chaara Wahiba, Rosenzwajg Michelle, Six Adrien, Prevel Nicolas, Mingozzi Federico, Wanschitz Julia, Musset Lucile, Charuel Jean-Luc, Eymard Bruno, Salomon Benoit, Duyckaerts Charles, Maisonobe Thierry, Dubourg Odile, Herson Serge, Klatzmann David, Benveniste Olivier

Abstract excerpt

OBJECTIVE: Sporadic inclusion body myositis (sIBM), the most frequent myositis in elderly patients, is characterized by the presence muscle inflammation and degeneration. We aimed at characterizing immune responses and regulatory T cells, considered key players in the maintenance of peripheral immune tolerance, in sIBM. METHODS: Serum and muscle tissue levels of 25 cytokines and phenotype of circulating immune...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24594700
DOI: 10.1371/journal.pone.0088788
PMCID: PMC3942319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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