Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants at 10p11 confer risk of Tetralogy of Fallot in Chinese of Nanjing.

PloS one - 1 Jan 2014

Xu Jing, Lin Yuan, Si Linjie, Jin Guangfu, Dai Juncheng, Wang Cheng, Chen Jiaping, Da Min, Hu Yuanli, Yi Chenlong, Hu Zhibin, Shen Hongbing, Mo Xuming, Chen Yijiang, Wang Xiaowei

Abstract excerpt

A recent genome-wide association study (GWAS) has identified a new subset of susceptibility loci of Tetralogy of Fallot (TOF), one form of cyanotic congenital heart disease (CHD), on chromosomes 10p11, 10p14, 12q24, 13q31, 15q13 and 16q12 in Europeans. In the current study, we conducted a case-control study in a Chinese population including 1,010 CHD cases [atrial septal defect (ASD), ventricular septal defect...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Chromosomes, Human, Pair 10

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Genotype

Share to Polymorphism, Single Nucleotide

Share to Tetralogy of Fallot

Source

Open in PubMed Open full text

Identifiers

PMID: 24594544
DOI: 10.1371/journal.pone.0089636
PMCID: PMC3940663

Genes

NRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants at 10p11 confer risk of Tetralogy of Fallot in Chinese of Nanjing.PMID 24594544Read ↗

Functional polymorphisms of the neuropilin 1 gene are associated with the risk of tetralogy of Fallot in a Chinese Han population.Semantic proximity Read ↗

Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot.Semantic proximity Read ↗

Sequencing of a Chinese tetralogy of Fallot cohort reveals clustering mutations in myogenic heart progenitors.Semantic proximity Read ↗

Rare copy number variations in adults with tetralogy of Fallot implicate novel risk gene pathways.Semantic proximity Read ↗

Detection of Genetic Variations in Children with Tetralogy of Fallot Using Whole Exome Sequencing Technology Integrated Bioinformatics Analysis.Semantic proximity Read ↗

Family-based whole-genome sequencing identifies compound heterozygous protein-coding and noncoding mutations in tetralogy of Fallot.Semantic proximity Read ↗

Deleterious genetic variants in <i>NOTCH1</i> are a major contributor to the incidence of non-syndromic Tetralogy of FallotSemantic proximity Read ↗

A common variant in the PTPN11 gene contributes to the risk of tetralogy of Fallot.Semantic proximity Read ↗

Exploring Genetic Diversity of SOD2 and POU5F1 for Congenital Heart Disease in the Southwest Chinese Population.Semantic proximity Read ↗

Genetic variations of VEGF gene were associated with tetralogy of fallot risk in a Chinese Han population.Semantic proximity Read ↗

Clinical genetic risk variants inform a functional protein interaction network for tetralogy of FallotSemantic proximity Read ↗

Clinical Genetic Risk Variants Inform a Functional Protein Interaction Network for Tetralogy of Fallot.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.