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Article

Maternal and Neonatal Plasma Micro<scp>RNA</scp> Biomarkers for Fetal Alcohol Exposure in an Ovine Model

3 Mar 2014

Abstract excerpt

BACKGROUND: Plasma or circulating miRNAs (cir miRNAs) have potential diagnostic value as biomarkers for a range of diseases. Based on observations that ethanol (EtOH) altered intracellular miRNAs during development, we tested the hypothesis that plasma miRNAs were biomarkers for maternal alcohol exposure, and for past in utero exposure, in the neonate. METHODS: Pregnant sheep were exposed to a binge model of EtOH...

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PMID: 24588274
DOI: 10.1111/acer.12378

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