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Article

Serum bilirubin concentration in healthy adult North-Europeans is strictly controlled by the UGT1A1 TA-repeat variants.

PloS one - 1 Jan 2014

Kringen Marianne K, Piehler Armin P, Grimholt Runa M, Opdal Mimi S, Haug Kari Bente F, Urdal Petter

Abstract excerpt

The major enzyme responsible for the glucuronidation of bilirubin is the uridine 5'-diphosphoglucose glucuronosyltransferase A1 (UGT1A1) enzyme, and genetic variation in the UGT1A1 gene is reported to influence the bilirubin concentration in the blood. In this study, we have investigated which gene-/haplotype variants may be useful for genetic testing of Gilbert's syndrome. Two groups of samples based on serum...

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Identifiers

PMID: 24587300
DOI: 10.1371/journal.pone.0090248
PMCID: PMC3938665

Genes

ABCC2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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