Article
A population survey of the glucose-6-phosphate dehydrogenase (G6PD) 563C>T (Mediterranean) mutation in Afghanistan.
PloS one - 1 Jan 2014
Jamornthanyawat Natsuda, Awab Ghulam R, Tanomsing Naowarat, Pukrittayakamee Sasithon, Yamin Fazel, Dondorp Arjen M, Day Nicholas P J, White Nicholas J, Woodrow Charles J, Imwong Mallika
Abstract excerpt
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a common inherited enzyme defect and an important problem in areas with Plasmodium vivax infection because of the risk of haemolysis following administration of primaquine to treat the liver forms of the parasite. We undertook a genotypic survey of 713 male individuals across nine provinces of Afghanistan in which malaria is found, four in the north and five...
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