Article
Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis.
Biochimica et biophysica acta - 1 Aug 2014
Tan Wenzhi, Pasinelli Piera, Trotti Davide
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with an adult onset characterized by loss of both upper and lower motor neurons. In ~10% of cases, patients developed ALS with an apparent genetic linkage (familial ALS or fALS). Approximately 20% of fALS displays mutations...
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