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Article

Arg347Cys polymorphism of α1a-adrenergic receptor in vasovagal syncope. Case-control study in a Mexican population.

Autonomic neuroscience : basic & clinical - 1 Jul 2014

Hernández-Pacheco Guadalupe, González-Hermosillo Antonio, Murata Chiharu, Yescas Petra, Espínola-Zavaleta Nilda, Martínez Martín, Serrano Héctor

Abstract excerpt

BACKGROUND: Vasovagal syncope is a common clinical condition, consequential to reduced cerebral blood flow resulting from a failure in cardiovascular homeostasis during orthostasis. Blood pressure regulation is the basis for syncope development. In this regulation, the α1a-adrenergic receptor plays a major role. Some studies have found a positive correlation between the Arg347Cys polymorphism of the...

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PMID: 24548768
DOI: 10.1016/j.autneu.2014.01.005

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