Article
Gonocyte transformation to spermatogonial stem cells occurs earlier in patients with undervirilisation syndromes.
Journal of pediatric surgery - 1 Feb 2014
Su Shu, Szarek Maciej, Vooght Abigail, Hutson John, Li Ruili
Abstract excerpt
AIM: Fertility post-orchidopexy is dependent on transformation of neonatal gonocytes (G) into adult dark spermatogonia at about 3 months, the same time as gonadotrophins stimulate androgen secretion. We examined how androgen blockade affects transformation of gonocytes to spermatogonial stem cells (SSC) during this period in patients with undervirilisation syndromes. METHODS: Patients with undervirilisation...
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