Article
Differential genes in adipocytes induced from polycystic and non-polycystic ovary syndrome-derived human embryonic stem cells.
Systems biology in reproductive medicine - 1 Jun 2014
Wang Fang, Liu Wei-Wei, Chen Xue-Mei, Kong Hui-Juan, Li Jing, Sun Ying-Pu
Abstract excerpt
We explored the molecular mechanisms of obesity and insulin resistance in patients with polycystic ovary syndrome (PCOS) using a human embryonic stem cell model (hESCs). Three PCOS-derived and one non-PCOS-derived hESC lines were induced into adipocytes, and then total RNA was extracted. The diff...
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