Article
Comparative genomic hybridization identifies virulence differences in Streptococcus suis.
PloS one - 1 Jan 2014
Zheng Han, Lan Ruiting, Zheng Xiao, Cui Zhigang, Liu Zhijie, Bai Xuemei, Ji Shaobo, Gottschalk Marcelo, Xu Jianguo
Abstract excerpt
Streptococcus suis is an important zoonotic pathogen. However, identification of virulent S. suis strains is complicated because of the high diversity of the species. Here we evaluated the genetic difference among S. suis strains using comparative genomic hybridization (CGH) and virulence variation in vivo and in vitro. We showed that different clades differed in their ability to activate TLR2/6 in vitro and...
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