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Article

Human papillomavirus 45 genetic variation and cervical cancer risk worldwide.

Journal of virology - 1 Apr 2014

Chen Alyce A, Heideman Daniëlle A M, Boon Debby, Gheit Tarik, Snijders Peter J F, Tommasino Massimo, Franceschi Silvia, Clifford Gary M

Abstract excerpt

UNLABELLED: Human papillomavirus 45 (HPV45) is a member of the HPV18-related alpha-7 species and accounts for approximately 5% of all cervical cancer cases worldwide. This study evaluated the genetic diversity of HPV45 and the association of HPV45 variants with the risk of cervical cancer by sequencing the entire E6 and E7 open reading frames of 300 HPV45-positive cervical samples from 36 countries. A total of 43...

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Identifiers

PMID: 24501412
DOI: 10.1128/JVI.03534-13
PMCID: PMC3993765

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