Article
HIV-1 diversity and drug resistance mutations among people seeking HIV diagnosis in voluntary counseling and testing sites in Rio de Janeiro, Brazil.
PloS one - 1 Jan 2014
Velasco-de-Castro Carlos A, Grinsztejn Beatriz, Veloso Valdiléa G, Bastos Francisco I, Pilotto José H, Fernandes Nilo, Morgado Mariza G
Abstract excerpt
The remarkable viral diversity remains a big challenge to the development of HIV vaccines and optimal therapy worldwide. In the latest years, as a consequence of the large expansion of highly active antiretroviral therapy (HAART) availability worldwide, an increase in transmitted drug resistance mutations (TDRM) has been observed, varying according the region. This study assessed HIV-1 diversity and TDRM profile...
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