Article
MiR-22 suppresses the proliferation and invasion of gastric cancer cells by inhibiting CD151.
Biochemical and biophysical research communications - 28 Feb 2014
Wang Xun, Yu Honggang, Lu Xinyao, Zhang Peng, Wang Minglin, Hu Yikui
Abstract excerpt
Gastric cancer (GC) is the second common cause of cancer-related death worldwide. microRNAs (miRNAs) play important roles in the carcinogenesis of GC. Here, we found that miR-22 was significantly decreased in GC tissue samples and cell lines. Ectopic overexpression of miR-22 remarkably suppressed cell proliferation and colony formation of GC cells. Moreover, overexpression of miR-22 significantly suppressed...
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