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Article

Expressions of miR-15a and its target gene <i>HSPA1B</i> in the spermatozoa of patients with varicocele

30 Jan 2014

Abstract excerpt

Hyperthermia and oxidative stresses are the two central elements contributing to varicocele-related sperm damage. Growing evidence indicates that microRNAs (miRNAs) are involved in the regulation of the heat and oxidative stress responses. In this study, we analyzed the expressions of several stress-related miRNAs in the sperm and found that the expression of miR-15a was significantly decreased in patients with...

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PMID: 24481955
DOI: 10.1530/rep-13-0656

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