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Article

Gene polymorphisms of micrornas in Helicobacter pylori-induced high risk atrophic gastritis and gastric cancer.

PloS one - 1 Jan 2014

Kupcinskas Juozas, Wex Thomas, Link Alexander, Leja Marcis, Bruzaite Indre, Steponaitiene Ruta, Juzenas Simonas, Gyvyte Ugne, Ivanauskas Audrius, Ancans Guntis, Petrenkiene Vitalija, Skieceviciene Jurgita, Kupcinskas Limas, Malfertheiner Peter

Abstract excerpt

BACKGROUND AND AIMS: MicroRNAs (miRNAs) are known for their function as translational regulators of tumor suppressor or oncogenes. Single nucleotide polymorphisms (SNPs) in miRNAs related genes have been shown to affect the regulatory capacity of miRNAs and were linked with gastric cancer (GC) and premalignant gastric conditions. The purpose of this study was to evaluate potential associations between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24475294
DOI: 10.1371/journal.pone.0087467
PMCID: PMC3903675

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