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Article

Genetic polymorphisms of miR-146a and miR-27a, H. pylori infection, and risk of gastric lesions in a Chinese population.

PloS one - 1 Jan 2013

Song Ming-yang, Su Hui-juan, Zhang Lian, Ma Jun-ling, Li Ji-you, Pan Kai-feng, You Wei-cheng

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) have been implicated in various human diseases. Single nucleotide polymorphisms (SNPs) in inflammation-related miRNA may play an important role in Helicobacter pylori (H. pylori)-induced gastric lesions. To evaluate the associations between miRNA SNPs, H. pylori and gastric lesions, a population-based study was conducted in Linqu County, China. METHODOLOGY/PRINCIPAL FINDINGS: Based...

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PMID: 23613822
DOI: 10.1371/journal.pone.0061250
PMCID: PMC3629121

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