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Mitochondrial cytopathies and cardiovascular disease

21 Jan 2014

Abstract excerpt

The global epidemic of cardiovascular disease remains the leading cause of death in the USA and across the world. Functional and structural integrity of mitochondria are essential for the physiological function of the cardiovascular system. The metabolic adaptation observed in normal heart is lost in the failing myocardium, which becomes progressively energy depleted leading to impaired myocardial contraction and...

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Identifiers

PMID: 24449718
DOI: 10.1136/heartjnl-2013-304657

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