Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

WNT10A mutations account for ¼ of population-based isolated oligodontia and show phenotypic correlations.

American journal of medical genetics. Part A - 1 Feb 2014

Arzoo Pakeeza Shaiq, Klar Joakim, Bergendal Birgitta, Norderyd Johanna, Dahl Niklas

Abstract excerpt

A large proportion (>50%) of patients with isolated oligodontia were recently reported with WNT10A mutations. We have analyzed a population-based cohort of 102 individuals diagnosed with non-syndromic oligodontia and a mean of 8.2 missing teeth. The cohort included 94 families and screening of WNT10A identified that 26 probands (27.7%) had at least one WNT10A variant. When we included the MSX1, PAX9, AXIN2, EDA,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Anodontia
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Phenotype

Share to Population Surveillance

Share to Sweden

Share to Wnt Proteins

Source

Identifiers

PMID: 24449199
DOI: 10.1002/ajmg.a.36243

Genes

AXIN2
EDA
EDAR
EDARADD
MSX1
PAX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

WNT10A mutations account for ¼ of population-based isolated oligodontia and show phenotypic correlations.PMID 24449199Read ↗

Mutations in WNT10A are present in more than half of isolated hypodontia cases.Semantic proximity Read ↗

WNT10B mutations associated with isolated dental anomalies.Semantic proximity Read ↗

Isolated oligodontia associated with mutations in EDARADD, AXIN2, MSX1, and PAX9 genes.Semantic proximity Read ↗

Mutations in WNT10A are frequently involved in oligodontia associated with minor signs of ectodermal dysplasia.Semantic proximity Read ↗

WNT10A and isolated hypodontia.Semantic proximity Read ↗

Analyses of oligodontia phenotypes and genetic etiologies.Semantic proximity Read ↗

Genotypic and phenotypic correlations in tooth agenesis: insights from WNT10A and EDA mutations in syndromic and non-syndromic forms.Semantic proximity Read ↗

Candidate gene analysis of tooth agenesis identifies novel mutations in six genes and suggests significant role for WNT and EDA signaling and allele combinations.Semantic proximity Read ↗

Clinical and genetic evaluation of a Chinese family with isolated oligodontia.Semantic proximity Read ↗

Dental and extra-oral clinical features in 41 patients with WNT10A gene mutations: A multicentric genotype-phenotype study.Semantic proximity Read ↗

Role of WNT10A in failure of tooth development in humans and zebrafish.Semantic proximity Read ↗

Molecular Basis and Clinical Spectrum of WNT10A-Related Oligodontia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.