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Article

HPV16 E6*II gene expression in intraepithelial cervical lesions as an indicator of neoplastic grade: a pilot study.

Medical oncology (Northwood, London, England) - 1 Mar 2014

Pastuszak-Lewandoska Dorota, Bartosińska-Dyc Anna, Migdalska-Sęk Monika, Czarnecka Karolina H, Nawrot Ewa, Domańska Daria, Szyłło Krzysztof, Brzeziańska Ewa

Abstract excerpt

Integration of the HPV genome into a host cell DNA leads to the deregulated overexpression of the viral E6 and E7 oncoproteins, and this is a key factor for progression from low-grade cervical lesions to high-grade lesions and invasive cervical cancer. The aim of our study was to analyze the expression levels of HPV E6*I/E6*II and E7 genes in cervical neoplasia of different grades. The analysis involved 10...

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PMID: 24436016
DOI: 10.1007/s12032-014-0842-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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