Prognostic value of HPV 16/18 genotyping and geminin mRNA quantification in low-grade cervical squamous intraepithelial lesion.

doi:10.1080/21655979.2021.2009959

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Article

Prognostic value of HPV 16/18 genotyping and geminin mRNA quantification in low-grade cervical squamous intraepithelial lesion.

Bioengineered - 1 Dec 2021

Zheng Ziwen, Yang Xiaorong, Yao Xinyu, Li Ling

Abstract excerpt

Low-grade cervical squamous intraepithelial lesion is a precancerous neoplasia that has appreciable probability to evolve into malignancy. To explore the prognostic value of HPV 16/18 genotyping and geminin mRNA quantification in predicting the progressiveness of LSIL. We recruited 212 participants who were negative for intraepithelial lesion or malignancy (NILM 76), low-grade squamous intraepithelial lesion...

Topics

Adult
Aged
Cell Line, Tumor
Disease Progression
Female
Follow-Up Studies
Geminin
Gene Expression Regulation, Neoplastic
Genotype
Human papillomavirus 16
Human papillomavirus 18

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Logistic Models

Middle Aged

Multivariate Analysis

Prognosis

RNA, Messenger

ROC Curve

Source

Open in PubMed Open full text

Identifiers

PMID: 34874226
DOI: 10.1080/21655979.2021.2009959
PMCID: PMC8810151

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