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Article

Deep RNA Sequencing Reveals Dynamic Regulation of Myocardial Noncoding RNAs in Failing Human Heart and Remodeling With Mechanical Circulatory Support

16 Jan 2014

Abstract excerpt

BACKGROUND: Microarrays have been used extensively to profile transcriptome remodeling in failing human heart, although the genomic coverage provided is limited and fails to provide a detailed picture of the myocardial transcriptome landscape. Here, we describe sequencing-based transcriptome profiling, providing comprehensive analysis of myocardial mRNA, microRNA (miRNA), and long noncoding RNA (lncRNA)...

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Share to Cardiac Fibrosis and Remodeling
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Share to Congenital heart defects research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24429688
DOI: 10.1161/circulationaha.113.003863

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