Article
Pilot of BRAF mutation analysis in indeterminate, suspicious and malignant thyroid FNA cytology.
Cytopathology : official journal of the British Society for Clinical Cytology - 1 Jun 2014
Johnson S J, Hardy S A, Roberts C, Bourn D, Mallick U, Perros P
Abstract excerpt
BACKGROUND: BRAF V600E mutation has been reported to show a high specificity for papillary thyroid carcinoma (PTC). Using this marker to upgrade 'indeterminate' or 'suspicious' thyroid fine needle aspiration (FNA) cytology to 'malignant' could potentially allow one-stage therapeutic total thyroidectomy. METHODS: For a 14-month period, FNA cytology specimens in the Thy3-5 categories, which are the UK equivalents...
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