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Article

One in four individuals of African-American ancestry harbors a 5.5kb deletion at chromosome 11q13.1.

Genomics - 1 Apr 2014

Zainabadi Kayvan, Jain Anuja V, Donovan Frank X, Elashoff David, Rao Nagesh P, Murty Vundavalli V, Chandrasekharappa Settara C, Srivatsan Eri S

Abstract excerpt

Cloning and sequencing of 5.5 kb deletion at chromosome 11q13.1 from the HeLa cells, tumorigenic hybrids and two fibroblast cell lines have revealed homologous recombination between AluSx and AluY resulting in the deletion of intervening sequences. Long-range PCR of the 5.5 kb sequence in 494 normal lymphocyte samples showed heterozygous deletion in 28.3% of African-American ancestry samples but only in 4.8% of...

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Identifiers

PMID: 24412158
DOI: 10.1016/j.ygeno.2014.01.001
PMCID: PMC4162346

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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