Article
Small deletion variants have stable breakpoints commonly associated with alu elements.
PloS one - 29 Aug 2008
de Smith Adam J, Walters Robin G, Coin Lachlan J M, Steinfeld Israel, Yakhini Zohar, Sladek Rob, Froguel Philippe, Blakemore Alexandra I F
Abstract excerpt
Copy number variants (CNVs) contribute significantly to human genomic variation, with over 5000 loci reported, covering more than 18% of the euchromatic human genome. Little is known, however, about the origin and stability of variants of different size and complexity. We investigated the breakpoints of 20 small, common deletions, representing a subset of those originally identified by array CGH, using Agilent...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.