Article
Genomic and phenotypic characterization of a wild medaka population: towards the establishment of an isogenic population genetic resource in fish.
G3 (Bethesda, Md.) - 20 Mar 2014
Spivakov Mikhail, Auer Thomas O, Peravali Ravindra, Dunham Ian, Dolle Dirk, Fujiyama Asao, Toyoda Atsushi, Aizu Tomoyuki, Minakuchi Yohei, Loosli Felix, Naruse Kiyoshi, Birney Ewan, Wittbrodt Joachim
Abstract excerpt
Oryzias latipes (medaka) has been established as a vertebrate genetic model for more than a century and recently has been rediscovered outside its native Japan. The power of new sequencing methods now makes it possible to reinvigorate medaka genetics, in particular by establishing a near-isogenic panel derived from a single wild population. Here we characterize the genomes of wild medaka catches obtained from a...
Topics
- Animals
- Genetics, Population
- Genome
- Genotype
- Heterozygote
- High-Throughput Nucleotide Sequencing
- Linkage Disequilibrium
- Microsatellite Repeats
- Oryzias
- Phenotype
- Phylogeny
- Polymorphism, Single Nucleotide