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[Relationship between clinical characteristics and myelodysplastic syndrome patients with isocitrate dehydrogenase gene mutations].

Zhonghua yi xue za zhi - 29 Oct 2013

Tong Hong-yan, Hu Chao, Yu Meng-xia, Ma Qiu-ling, Chen Fei-fei, Ye Li, Wei Ju-ying, Xu Gai-xiang, Mao Li-ping, Li Ying, Jin Jie

Abstract excerpt

OBJECTIVE: To assess the prevalence and clinical characteristics of isocitrate dehydrogenase 1 and 2 (IDH 1 and IDH2) gene mutations in myelodysplastic syndrome (MDS) patients. METHODS: Pretreatment bone marrow specimens were enriched for mononuclear cells in 108 adult patients with de novo MDS from January 2006 to August 2012. Genomic DNA was extracted from mononuclear cells. And PCR and direct sequencing were...

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Identifiers

PMID: 24405536

Genes

IDH2
IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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