Metabolite transfer with the fermentation product 2,3-butanediol enhances virulence by <i>Pseudomonas aeruginosa</i>

Abstract excerpt

The respiratory tract of cystic fibrosis (CF) patients harbor persistent microbial communities (CF airway microbiome) with Pseudomonas aeruginosa emerging as a dominant pathogen. Within a polymicrobial infection, interactions between co-habitant microbes can be important for pathogenesis, but even when considered, these interactions are not well understood. Here, we show with in vitro experiments that, compared...

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