Article
Detecting novel SNPs and breed-specific haplotypes at calpastatin gene in Iranian fat- and thin-tailed sheep breeds and their effects on protein structure.
Gene - 1 Mar 2014
Aali Mohsen, Moradi-Shahrbabak Mohammad, Moradi-Shahrbabak Hosein, Sadeghi Mostafa
Abstract excerpt
Calpastatin has been introduced as a potential candidate gene for growth and meat quality traits. In this study, genetic variability was investigated in the exon 6 and its intron boundaries of ovine CAST gene by PCR-SSCP analysis and DNA sequencing. Also a protein sequence and structural analysis were performed to predict the possible impact of amino acid substitutions on physicochemical properties and structure...
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