Article
Interplay between three RND efflux pumps in doxycycline-selected strains of Burkholderia thailandensis.
PloS one - 1 Jan 2013
Biot Fabrice Vincent, Lopez Mélanie Monique, Poyot Thomas, Neulat-Ripoll Fabienne, Lignon Sabrina, Caclard Arnaud, Thibault François Michel, Peinnequin Andre, Pagès Jean-Marie, Valade Eric
Abstract excerpt
BACKGROUND: Efflux systems are involved in multidrug resistance in most Gram-negative non-fermentative bacteria. We have chosen Burkholderia thailandensis to dissect the development of multidrug resistance phenotypes under antibiotic pressure. METHODOLOGY/PRINCIPAL FINDINGS: We used doxycycline selection to obtain several resistant B. thailandensis variants. The minimal inhibitory concentrations of a large panel...
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