Article
Comparison of Two ELISA Methods and Mass Spectrometry for Measurement of Vitamin D-Binding Protein: Implications for the Assessment of Bioavailable Vitamin D Concentrations Across Genotypes.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jun 2016
Denburg Michelle R, Hoofnagle Andrew N, Sayed Samir, Gupta Jayanta, de Boer Ian H, Appel Lawrence J, Durazo-Arvizu Ramon, Whitehead Krista, Feldman Harold I, Leonard Mary B
Abstract excerpt
Studies using vitamin D-binding protein (DBP) concentrations to estimate free and bioavailable vitamin D have increased dramatically in recent years. Combinations of two single-nucleotide polymorphisms (SNPs) produce three major DBP isoforms (Gc1f, Gc1s, and Gc2). A recent study showed that DBP concentrations quantified by liquid chromatography-tandem mass spectrometry (LC-MS/MS) did not differ by race, whereas a...
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