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Article

Defining early-onset kidney cancer: implications for germline and somatic mutation testing and clinical management.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Feb 2014

Shuch Brian, Vourganti Srinivas, Ricketts Christopher J, Middleton Lindsay, Peterson James, Merino Maria J, Metwalli Adam R, Srinivasan Ramaprasad, Linehan W Marston

Abstract excerpt

PURPOSE: Approximately 5% to 8% of renal cell carcinoma (RCC) is hereditary. No guidelines exist for patient selection for RCC germline mutation testing. We evaluate how age of onset could indicate the need for germline mutation testing for detection of inherited forms of kidney cancer. PATIENTS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24378414
DOI: 10.1200/JCO.2013.50.8192
PMCID: PMC3912328

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24378414-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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