Article
Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs.
Nature communications - 1 Jan 2013
Villarroya-Beltri Carolina, Gutiérrez-Vázquez Cristina, Sánchez-Cabo Fátima, Pérez-Hernández Daniel, Vázquez Jesús, Martin-Cofreces Noa, Martinez-Herrera Dannys Jorge, Pascual-Montano Alberto, Mittelbrunn María, Sánchez-Madrid Francisco
Abstract excerpt
Exosomes are released by most cells to the extracellular environment and are involved in cell-to-cell communication. Exosomes contain specific repertoires of mRNAs, microRNAs (miRNAs) and other non-coding RNAs that can be functionally transferred to recipient cells. However, the mechanisms that c...
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