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Fetal Fraction Estimate in Twin Pregnancies Using Directed Cell-Free DNA Analysis

7 Dec 2013

Abstract excerpt

OBJECTIVE: To estimate fetal fraction (FF) in monozygotic and dizygotic twin pregnancies. METHODS: Maternal plasma samples were obtained from 35 monochorionic twin pregnancies with male fetuses (monozygotic) and 35 dichorionic pregnancies discordant for fetal sex (dizygotic) at 11-13 weeks' gestation. Cell-free DNA was extracted and chromosome-selective sequencing with digital analysis of selected regions...

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Share to Assisted Reproductive Technology and Twin Pregnancy
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PMID: 24356438
DOI: 10.1159/000355653

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