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The effects of poly L-lactic acid nanofiber scaffold on mouse spermatogonial stem cell culture

1 Nov 2013

Abstract excerpt

INTRODUCTION: A 3D-nanofiber scaffold acts in a similar way to the extracellular matrix (ECM)/basement membrane that enhances the proliferation and self-renewal of stem cells. The goal of the present study was to investigate the effects of a poly L-lactic acid (PLLA) nanofiber scaffold on frozen-thawed neonate mouse spermatogonial stem cells (SSCs) and testis tissues. METHODS: The isolated spermatogonial cells...

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PMID: 24348035
DOI: 10.2147/ijn.s45535

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