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Article

TLR4-dependant immune response, but not hepatitis B virus reactivation, is important in radiation-induced liver disease of liver cancer radiotherapy.

Cancer immunology, immunotherapy : CII - 1 Mar 2014

Wu Zhi-Feng, Zhou Xiao-Hui, Hu Yun-Wen, Zhou Le-Yuan, Gao Ya-Bo, Peng Xiu-Hua, Yang Xiao-Hua, Zhang Jian-Ying, Hu Yong, Zeng Zhao-Chong

Abstract excerpt

Toll-like receptor 4 (TLR4) is an important trigger of the immune response against hepatitis B virus (HBV) infection and liver injuries. The roles of HBV reactivation versus TLR4-dependant immune response may be critical factors in preventing radiation-induced liver diseases (RILDs) after liver cancer radiotherapy. This study consists of three phases. In the primary phase, livers of mutant TLR4 (TLR4(-)) mice...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24337704
DOI: 10.1007/s00262-013-1504-9
PMCID: PMC11029679

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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