Article
Phosphatidylinositol 4,5-bisphosphate influences PIN polarization by controlling clathrin-mediated membrane trafficking in Arabidopsis.
The Plant cell - 1 Dec 2013
Ischebeck Till, Werner Stephanie, Krishnamoorthy Praveen, Lerche Jennifer, Meijón Mónica, Stenzel Irene, Löfke Christian, Wiessner Theresa, Im Yang Ju, Perera Imara Y, Iven Tim, Feussner Ivo, Busch Wolfgang, Boss Wendy F, Teichmann Thomas, Hause Bettina, Persson Staffan, Heilmann Ingo
Abstract excerpt
The functions of the minor phospholipid phosphatidylinositol-4,5-bisphosphate [PtdIns(4,5)P2] during vegetative plant growth remain obscure. Here, we targeted two related phosphatidylinositol 4-phosphate 5-kinases (PI4P 5-kinases) PIP5K1 and PIP5K2, which are expressed ubiquitously in Arabidopsis thaliana. A pip5k1 pip5k2 double mutant with reduced PtdIns(4,5)P2 levels showed dwarf stature and phenotypes...
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