Article
Antagonistic regulation of PIN phosphorylation by PP2A and PINOID directs auxin flux.
Cell - 21 Sept 2007
Michniewicz Marta, Zago Marcelo K, Abas Lindy, Weijers Dolf, Schweighofer Alois, Meskiene Irute, Heisler Marcus G, Ohno Carolyn, Zhang Jing, Huang Fang, Schwab Rebecca, Weigel Detlef, Meyerowitz Elliot M, Luschnig Christian, Offringa Remko, Friml Jirí
Abstract excerpt
In plants, cell polarity and tissue patterning are connected by intercellular flow of the phytohormone auxin, whose directional signaling depends on polar subcellular localization of PIN auxin transport proteins. The mechanism of polar targeting of PINs or other cargos in plants is largely unidentified, with the PINOID kinase being the only known molecular component. Here, we identify PP2A phosphatase as an...
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