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Article

Epigenetic Regulation of αA-crystallin in High Myopia-Induced Dark Nuclear Cataract

3 Dec 2013

Abstract excerpt

PURPOSE: To assess the etiology of early-onset dark nucleus in high-myopic patients and its relationship with the epigenetic regulation of αA-crystallin (CRYAA). METHODS: We reviewed clinical data from patients who underwent cataract surgery at our center in 2012. Lens epithelial samples were collected during capsulorhexis, whereas young lens epithelium was donated. Cataract type and severity were graded...

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PMID: 24312600
DOI: 10.1371/journal.pone.0081900

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