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Article

Involvement of and interaction between WNT10A and EDA mutations in tooth agenesis cases in the Chinese population.

PloS one - 1 Jan 2013

He Huiying, Han Dong, Feng Hailan, Qu Hong, Song Shujuan, Bai Baojing, Zhang Zhenting

Abstract excerpt

BACKGROUND: Dental agenesis is the most common, often heritable, developmental anomaly in humans. Although WNT10A gene mutations are known to cause rare syndromes associated with tooth agenesis, including onycho-odontodermal dysplasia (OODD), Schöpf-Schulz-Passarge syndrome (SSPS), hypohidrotic ectodermal dysplasia (HED), and more than half of the cases of isolated oligodontia recently, the genotype-phenotype...

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Source

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Identifiers

PMID: 24312213
DOI: 10.1371/journal.pone.0080393
PMCID: PMC3842385

Genes

EDA
EDAR
EDARADD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Involvement of and interaction between WNT10A and EDA mutations in tooth agenesis cases in the Chinese population.PMID 24312213Read ↗

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Compound heterozygous WNT10A missense variations exacerbated the tooth agenesis caused by hypohidrotic ectodermal dysplasia.Semantic proximity Read ↗

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