Article
Effect of high-dose N-acetylcysteine on airway geometry, inflammation, and oxidative stress in COPD patients.
International journal of chronic obstructive pulmonary disease - 1 Jan 2013
De Backer Jan, Vos Wim, Van Holsbeke Cedric, Vinchurkar Samir, Claes Rita, Parizel Paul M, De Backer Wilfried
Abstract excerpt
BACKGROUND: Previous studies have demonstrated the potential beneficial effect of N-acetylcysteine (NAC) in chronic obstructive pulmonary disease (COPD). However, the required dose and responder phenotype remain unclear. The current study investigated the effect of high-dose NAC on airway geometry, inflammation, and oxidative stress in COPD patients. Novel functional respiratory imaging methods combining...
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